Parasites: A User's Guide

Helminthic Therapy

Community

Helminth Therapy Companies

  • Autoimmune Therapies (helminth supply company founded by Jasper Lawrence, and home of the helminthic therapy community message board)
  • Ovamed (helminth supply company out of Germany)
  • Worm Therapy (helminth supply company out of Tijuana)

Success Stories

  • Download PDF HERE (list compiled by John Scott)

Blogs

List compiled with help from Debora Wade and John Scott

Disease-specific blogs (compiled by John Scott)

Allergy

Food allergy/intolerance


Crohns' disease


Ulcerative colitis

Books

Helminths in the media

List compiled in part by Autoimmune Therapies and used with permission.

Academic research on helminths and the immune system

List compiled by Donna L. Beales, M.L.I.S., and used with permission.

1.

Trichuris suis ova therapy for allergic rhinitis: A randomized, double-blind, placebo-controlled clinical trial.

 

Bager P, Arnved J, Rønborg S, Wohlfahrt J, Poulsen LK, Westergaard T, Petersen HW, Kristensen B, Thamsborg S, Roepstorff A, Kapel C, Melbye M.

 

J Allergy Clin Immunol. 2009 Oct 2. [Epub ahead of print]

 

PMID: 19800680 [PubMed - as supplied by publisher]

 

Related articles

2.

Interactions between helminth parasites and allergy.

 

Cooper PJ.

 

Curr Opin Allergy Clin Immunol. 2009 Feb;9(1):29-37. Review.

 

PMID: 19106698 [PubMed - indexed for MEDLINE]

 

Related articles Free article

3.

Helminthic therapy: using worms to treat immune-mediated disease.

 

Elliott DE, Weinstock JV.

 

Adv Exp Med Biol. 2009;666:157-66.

 

PMID: 20054982 [PubMed - in process]

 

 

4.

Can helminths or helminth-derived products be used in humans to prevent or treat allergic diseases?

 

Erb KJ.

 

Trends Immunol. 2009 Feb;30(2):75-82. Epub 2009 Jan 8.

 

PMID: 19138565 [PubMed - indexed for MEDLINE]

 

Related articles

5.

Roles for Inflammation and Regulatory t Cells in Colon Cancer.

 

Erdman SE, Poutahidis T.

 

Toxicol Pathol. 2009 Dec 17. [Epub ahead of print]

 

PMID: 20019355 [PubMed - as supplied by publisher]

 

Related articles

6.

Safety of hookworm infection in individuals with measurable airway responsiveness: a randomized placebo-controlled feasibility study.

 

Feary J, Venn A, Brown A, Hooi D, Falcone FH, Mortimer K, Pritchard DI, Britton J.

 

Clin Exp Allergy. 2009 Jul;39(7):1060-8. Epub 2009 Apr 20.

 

PMID: 19400893 [PubMed - indexed for MEDLINE]

 

Related articles Free article

7.

Experimental hookworm infection: a randomized placebo-controlled trial in asthma.

 

Feary JR, Venn AJ, Mortimer K, Brown AP, Hooi D, Falcone FH, Pritchard DI, Britton JR.

 

Clin Exp Allergy. 2009 Dec 16. [Epub ahead of print]

 

PMID: 20030661 [PubMed - as supplied by publisher]

 

Related articles

8.

Establishment and characterization of continuous hematopoietic progenitors-derived pig normal mast cell lines.

 

Femenia F, Arock M, Leriche L, Delouis C, Millet G, Ben Hamouda N, Cote M, Alliot A, Lilin T, Pinton A, Iannucceli N, Parodi AL, Boireau P.

 

Life Sci. 2005 Jul 1;77(7):808-23.

 

PMID: 15896811 [PubMed - indexed for MEDLINE]

 

Related articles

9.

Reduced helminth burden increases allergen skin sensitization but not clinical allergy: a randomized, double-blind, placebo-controlled trial in Vietnam.

 

Flohr C, Tuyen LN, Quinnell RJ, Lewis S, Minh TT, Campbell J, Simmons C, Telford G, Brown A, Hien TT, Farrar J, Williams H, Pritchard DI, Britton J.

 

Clin Exp Allergy. 2009 Sep 15. [Epub ahead of print]

 

PMID: 19758373 [PubMed - as supplied by publisher]

 

Related articles

10.

Do helminth parasites protect against atopy and allergic disease?

 

Flohr C, Quinnell RJ, Britton J.

 

Clin Exp Allergy. 2009 Jan;39(1):20-32. Review.

 

PMID: 19128351 [PubMed - indexed for MEDLINE]

 

Related articles

11.

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

 

Fumagalli M, Pozzoli U, Cagliani R, Comi GP, Riva S, Clerici M, Bresolin N, Sironi M.

 

J Exp Med. 2009 Jun 8;206(6):1395-408. Epub 2009 May 25.

 

PMID: 19468064 [PubMed - indexed for MEDLINE]

 

Related articles Free article

12.

New and emerging therapies for inflammatory bowel diseases.

 

Grimm MC.

 

J Gastroenterol Hepatol. 2009 Oct;24 Suppl 3:S69-74. Review.

 

PMID: 19799702 [PubMed - indexed for MEDLINE]

 

Related articles

13.

Mansonella perstans--the importance of an endosymbiont.

 

Hoerauf A.

 

N Engl J Med. 2009 Oct 8;361(15):1502-4. No abstract available.

 

PMID: 19812409 [PubMed - indexed for MEDLINE]

 

Related articles

14.

Obesity - extending the hygiene hypothesis.

 

Isolauri E, Kalliomäki M, Rautava S, Salminen S, Laitinen K.

 

Nestle Nutr Workshop Ser Pediatr Program. 2009;64:75-85; discussion 85-9, 251-7. Epub 2009 Aug 19.

 

PMID: 19710516 [PubMed - indexed for MEDLINE]

 

Related articles

15.

Infections and autoimmunity--friends or foes?

 

Kivity S, Agmon-Levin N, Blank M, Shoenfeld Y.

 

Trends Immunol. 2009 Aug;30(8):409-14. Epub 2009 Jul 28. Review.

 

PMID: 19643667 [PubMed - indexed for MEDLINE]

 

Related articles

16.

Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis.

 

Maizels RM.

 

Parasitology. 2009 Oct;136(12):1549-64. Epub 2009 May 22. Review.

 

PMID: 19460185 [PubMed - indexed for MEDLINE]

 

Related articles

17.

Trichuris suis excretory secretory products (ESP) elicit interleukin-6 (IL-6) and IL-10 secretion from intestinal epithelial cells (IPEC-1).

 

Parthasarathy G, Mansfield LS.

 

Vet Parasitol. 2005 Aug 10;131(3-4):317-24.

 

PMID: 15978725 [PubMed - indexed for MEDLINE]

 

Related articles

18.

Review series on helminths, immune modulation and the hygiene hypothesis: the broader implications of the hygiene hypothesis.

 

Rook GA.

 

Immunology. 2009 Jan;126(1):3-11. Review.

 

PMID: 19120493 [PubMed - indexed for MEDLINE]

 

Related articles Free article

19.

The hygiene hypothesis and psychiatric disorders.

 

Rook GA, Lowry CA.

 

Trends Immunol. 2008 Apr;29(4):150-8. Epub 2008 Mar 6.

 

PMID: 18328783 [PubMed - indexed for MEDLINE]

 

Related articles

20.

The hygiene hypothesis and the increasing prevalence of chronic inflammatory disorders.

 

Rook GA.

 

Trans R Soc Trop Med Hyg. 2007 Nov;101(11):1072-4. Epub 2007 Jul 9. Review.

 

PMID: 17619029 [PubMed - indexed for MEDLINE]

 

Related articles

21.

Therapeutic colonization with Trichuris suis.

 

Summers RW, Elliott DE, Weinstock JV.

 

Arch Pathol Lab Med. 2006 Dec;130(12):1753; author reply 1753-4. No abstract available.

 

PMID: 17149943 [PubMed - indexed for MEDLINE]

 

Related articles

22.

Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses.

 

Walsh KP, Brady MT, Finlay CM, Boon L, Mills KH.

 

J Immunol. 2009 Aug 1;183(3):1577-86. Epub 2009 Jul 8.

 

PMID: 19587018 [PubMed - indexed for MEDLINE]

 

Related articles

23.

Helminths and the IBD hygiene hypothesis.

 

Weinstock JV, Elliott DE.

 

Inflamm Bowel Dis. 2009 Jan;15(1):128-33. Review.

 

PMID: 18680198 [PubMed - indexed for MEDLINE]

 

Related articles Free article

24.

Early exposure of infants to GI nematodes induces Th2 dominant immune responses which are unaffected by periodic anthelminthic treatment.

 

Wright VJ, Ame SM, Haji HS, Weir RE, Goodman D, Pritchard DI, Mohamed MR, Haji HJ, Tielsch JM, Stoltzfus RJ, Bickle QD.

 

PLoS Negl Trop Dis. 2009;3(5):e433. Epub 2009 May 19.

 

PMID: 19436745 [PubMed - in process]

 

Related articles Free article

25.

Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.

 

Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E.

 

Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L67-78. Epub 2009 Sep 25.

 

PMID: 19783640 [PubMed - indexed for MEDLINE]

 

Related articles

26.

Parasitic infection and autoimmunity.

 

Zandman-Goddard G, Shoenfeld Y.

 

Lupus. 2009 Nov;18(13):1144-8. Review.

 

PMID: 19880560 [PubMed - indexed for MEDLINE]

 

Related articles